https://zhengzhangxrt.com/tags/nonmalignant-diseases/ Recent content in Nonmalignant-Diseases on Zheng Zhang, Ph.D., DABR Hugo en Sat, 26 Apr 2025 00:00:00 +0000 https://zhengzhangxrt.com/project/low-dose-ratiation-therapy-osteoarthritis/ Sat, 26 Apr 2025 00:00:00 +0000 https://zhengzhangxrt.com/project/low-dose-ratiation-therapy-osteoarthritis/ Project in progress. Details to be added later… Low dose radiation therapy (LDRT) is an effective symptom management option for osteoarthritis (OA). However, the mechanistic picture of this treatment is unclear. Existing pre-clinical studies have established the anti-inflammatory effects of LDRT at the cellular level, but a deeper understanding at the molecular level is needed. With this project, we aim to identify the anti-inflammatory molecular pathways triggered by LDRT. This project is a physics-biology collaboration, leveraging physics expertise in microtomographic imaging (microCT) and small animal radiation research platform (SARRP), to investigate a novel model system.